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Salbutamol Sulfate Inhaler: Rapid Relief for Asthma and COPD

更新時間：2025-06-18

價格： 7 元/個

地區(qū)：上海市

是否提供樣品：否

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產(chǎn)品詳情

產(chǎn)品關(guān)鍵詞： Salbutamol Sulfate Inhaler,Bronchodilator,Asthma Relief,COPD Treatment,Respiratory Inhalation Aerosol

是否為生產(chǎn)商：是

主要銷售市場：中國,北美洲,中/南美洲,西歐,大洋洲,亞洲,中東,非洲

產(chǎn)品描述：

Mechanism of Action

Salbutamol sulfate inhalation aerosol is a selective β?-adrenergic receptor agonist. Its primary mechanism involves binding to β?-receptors located on bronchial smooth muscle cells. Activation of these receptors leads to increased production of cyclic adenosine monophosphate (cAMP), which subsequently reduces intracellular calcium levels. This results in the relaxation of smooth muscles and bronchodilation, thereby alleviating symptoms of bronchial spasms. Additionally, salbutamol inhibits the release of inflammatory mediators from mast cells and other sensitized cells, further reducing bronchial spasms.

Applications

Salbutamol sulfate inhalation aerosol is widely used in the treatment of respiratory conditions characterized by bronchial spasms. Its primary applications include:

Asthma: It provides rapid relief during acute asthma attacks and is also used to prevent exercise-induced asthma.
Chronic Obstructive Pulmonary Disease (COPD): It helps in managing bronchial spasms associated with COPD, improving respiratory function.
Other Respiratory Conditions: It is also used to treat bronchial spasms associated with chronic bronchitis and other respiratory diseases.

Future Prospects

The future outlook for salbutamol sulfate inhalation aerosol is promising due to its proven efficacy and safety profile. Ongoing research is exploring its potential in combination therapies for more effective management of respiratory diseases. Additionally, advancements in inhaler technology are aimed at improving drug delivery and patient compliance. The increasing prevalence of asthma and COPD, particularly in developing countries, is expected to drive the demand for this medication.

Dosage and Administration

Adults:

Relief of Acute Symptoms: The initial dose is 100-200 μg (1-2 puffs), which can be repeated every 4-8 hours as needed. The maximum recommended dose is 8 puffs within 24 hours.
Prevention of Symptoms: For exercise-induced asthma, 1-2 puffs should be taken 10-15 minutes before the activity.
Children:
Relief of Acute Symptoms: The recommended dose is 1 puff (100 μg), which can be increased to 2 puffs if necessary.
Prevention of Symptoms: Similar to adults, 1-2 puffs should be taken 10-15 minutes before exposure to allergens or exercise.
Special Populations:
Elderly Patients: The initial dose should be lower than that for adults and adjusted based on response.
Patients with Liver or Kidney Impairment: Dose adjustments may be necessary to prevent drug accumulation.
Instructions for Use:
The inhaler should be used orally. Patients should shake the canister well before use and prime the inhaler by releasing four test sprays into the air if it has not been used for more than two weeks.
The patient should exhale completely, place the mouthpiece in their mouth, and press the canister while inhaling deeply. After inhalation, the patient should hold their breath for about 10 seconds before exhaling.

Storage

Salbutamol sulfate inhalation aerosol should be stored at temperatures below 30°C (86°F), protected from light and extreme cold. The canister should not be punctured, broken, or burned, even if it appears empty. It is also important to keep the inhaler out of reach of children.

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